Klamath Tribal Health & Family Services is a division of the Klamath Tribes and is responsible for providing healthcare services to the Native American population who reside in Klamath County. Any person living in Klamath County who is able to provide proof of their Native American heritage is eligible to receive healthcare services at The Klamath Tribes Wellness Center.

The Indian Health Service (I.H.S.) is an agency within the U.S. Department of Health & Human Services. It is responsible for providing federal health services to American Indians and Alaska Natives. The provision of health services to members of federally-recognized tribes grew out of the special government-to-government relationship between the federal government and Indian tribes. This relationship, established in 1787, is based on Article I, Section 8 of the Constitution, and has been given form and substance by numerous treaties, laws, Supreme Court decisions, and Executive Orders. The IHS is the principal federal health care provider and health advocate for Indian people. The mission of the Indian Health Service is to raise the physical, mental, social, and spiritual health of American Indians and Alaska Natives to the highest level. Under the provisions of Public Law 93-638, The Klamath Tribes contract with the Indian Health Service to administer individual programs and services the I.H.S. would otherwise provide (referred to as a Title I Self-Determination Contract).